Our gut bacteria play an incredibly complex and critical role in helping us thrive. The microbiome affects everything from digestion to the immune system, hormones, skin health and even mental wellbeing.
synbiotic dual cap.
23x more successful at reaching the gut alive. One potent daily dosage contains 11 clinically trialled bacterial strains alongside FOS fibre, vitamin D, zinc and biotin. Dual Cap® technology ensures 23x higher survivability, delivering 50 billion bacteria alive and in an effective condition. Just once a day, every day. 50 billion CFU. Best taken daily over a minimum of 3 months.
synbiotic dual cap.
4.59 / 5
4.59 / 5
23x more successful at reaching the gut alive.
One potent daily dosage contains 11 clinically trialled bacterial strains alongside FOS fibre, vitamin D, zinc and biotin. Dual Cap® technology ensures 23x higher survivability, delivering 50 billion bacteria alive and in an effective condition. Just once a day, every day.
50 billion CFU. Best taken daily over a minimum of 3 months.
One potent daily dosage contains 11 clinically trialled bacterial strains alongside FOS fibre, vitamin D, zinc and biotin. Dual Cap® technology ensures 23x higher survivability, delivering 50 billion bacteria alive and in an effective condition. Just once a day, every day.
1-month subscription
£54.99/mo
(1mo = £54.99)
30 servings
£1.83 per serving
most popular.
3-month subscription
Save 18%
£44.99/mo
(3mo = £134.99)
90 servings
£1.50 per serving
Refill sachets after 1st subscription
Money-back guarantee
best value.
6-month subscription
Save 27%
£39.99/mo
(6mo = £239.99)
180 servings
£1.33 per serving
Refill sachets after 1st subscription
Money-back guarantee
start your journey.
1-month subscription
30 servings
£1.83 per serving
£54.99
3-month subscription
90 servings
£1.50 per serving
Save 18%
£164.97
£134.99
6-month subscription
180 servings
£1.33 per serving
Save 27%
£329.94
£239.99
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Free delivery on all UK orders over £40.
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90 day money-back guarantee.
Skip, pause or cancel your subscription anytime
Skip, pause or cancel your subscription anytime
The British Society of Gastroenterology recommends taking a new bacterial product for a minimum of 3 months, which is why we've made it easy (and more affordable) to subscribe. Skip, pause or cancel anytime from your subscription page.
90 day money-back guarantee
90 day money-back guarantee
We truly believe we have created the best digestive health supplement on the market. Therefore if you don't see results after taking our synbiotic for 90 days (once a day, every day) our money-back guarantee exists to protect you. Read more on our Policies Page.
Free delivery on all UK orders
Free delivery on all UK orders
EU and International shipping rates vary, and you may also need to pay local taxes. For more information on delivery times and rates visit our Shipping Page.
90 day money-back guarantee
90 day money-back guarantee
We truly believe we have created the best digestive health supplement on the market. Therefore if you don't see results after taking our synbiotic for 90 days (once a day, every day) our money-back guarantee exists to protect you. Read more on our Policies Page.
How long do I need to take the synbiotic dual cap for?
How long do I need to take the synbiotic dual cap for?
We recommend taking one capsule a day for a minimum of 3 months. This is how long your microbiome needs to adjust to the new bacteria, as also recommended by the British Society of Gastroenterology to anyone trying a new bacterial product.
Can I take other supplements alongside this for my gut or is Epetome enough?
Can I take other supplements alongside this for my gut or is Epetome enough?
The synbiotic dual cap. has been designed to provide one potent dosage of 50 billion live bacteria in one capsule, from 11 unique strains, alongside other vitamins and minerals that support overall gut health. Therefore as far as live bacteria supplements go, our synbiotic dual cap. should be enough.
Eco-friendly packaging info
Eco-friendly packaging info
Your first order arrives in a reusable jar. Keep your jar. From your second order onwards, refill sachets will arrive every three or six months for effortless top ups.
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
“Now my tummy problems are non-existent and generally feel my gut is more at peace.”
“Epetōme is seriously impressive. I've noticed great improvements to my digestion and overall wellbeing.”
"With 50 billion colony-forming units (CFU), it's one of the most potent supplements on the market."
"You might feel as if you stumbled upon a revolutionary hack or 'magic pill'."
How our lifestyle choices impact our gut microbiome.
helping you to look after your gut.
Our capsule takes intricate health science and transforms it into one simple daily ritual, making optimal gut health an accessible goal for everyone.
helping you to look after your gut.
Our capsule takes intricate health science and transforms it into one simple daily ritual, making optimal gut health an accessible goal for everyone.
your unique journey.
Your microbiome is as unique as you are - it's as unique as your fingerprint. Therefore, your journey will be unique to you too. Here's what you may expect, with some variance to be expected.
Day 0
Your new daily habit starts. Remember, just once a day, every day.
Week 1
Your body starts getting acquainted with its new guests.
Month 1
You have cemented your new routine, with some fluctuations still possible.
Month 3
Your body starts to adapt, finding tempo and balance.
Month 6
Personal discoveries? We’d love to hear them.
optimised by technology.
Epetōme's synbiotic dual cap. is the meeting point of science and simplicity. 23x higher absorption than non-encapsulated, its unique capsule-in-capsule design ensures targeted delivery of ingredients within the gut, where the microbiome thrives.
The transparent outer shell is designed to break down in your stomach, releasing fructooligosaccharides (FOS) fibre, which act as food for the live bacteria. It also contains Vitamin D3, Biotin and Zinc, all of which have been included for their role in supporting a healthy gut.
outer
Not visible to the naked eye, within the green inner capsule are 50 billion live bacteria. Protected by the outer shell as it makes its way through the stomach, this inner capsule is able to continue through the gastro-intestinal tract, breaking down in the intestines and releasing the live cultures into your gut microbiome.
inner
what sets epetōme apart?
pre + pro = synbiotic dual cap.
non-encapsulated
standard capsules
potency.
CFU/g (billion)
50
10
10-20
synbiotic dual cap technology.
diversity.
number of bacterial strains
11
4
7-14
prebiotic included.
vitamins & minerals included.
convenient storage.
yes
cupboard
no
refrigerated
yes
cupboard
convenient consumption.
yes
1 a day
yes
70ml a day
no
3+ per day
price per serving.
starting from prices
£1.33
£1.43
£1.33
Epetōme looks different, and for good reason. Just one potent daily dose of biotics with advanced synbiotic dual cap technology, to ensure each ingredient is delivered with precision - to the right place, at the right time.
Emily answers your questions about Epetōme:
The world of supplements and gut health can be confusing. So below I have answered some of your most asked questions.
What exactly is our microbiome?
View Transcript
What’s the difference between a prebiotic and a probiotic?
View Transcript
Should I take a supplement for my gut health?
View Transcript
What makes our synbiotic dual cap unique?
View Transcript
What can I expect from taking the synbiotic dual cap?
View Transcript
Why does survivability matter and how does the synbiotic dual cap achieve it?
View Transcript
Why does Epetōme cost more than a standard probiotic?
Because you’re paying for both what’s inside and how it’s protected. Epetōme uses trademarked strains with research behind them, so you know exactly which bacteria you’re getting. It combines 50 billion CFU from 11 individually named strains with FOS fibre, vitamin D, zinc and biotin in one daily capsule. Its Dual Cap® technology is designed to protect the live bacteria through their journey to the gut. SHIME® testing found that the synbiotic dual cap had 12x higher survivability rates than the non-encapsulated, and 23x higher than the leading powder, offering more than a high bacteria count on the label.
Is Epetōme worth the price?
From £1.33 a day on a 6-month subscription with free UK delivery, Epetōme brings together ingredients you’d otherwise need around five separate supplements to get, making your daily routine simpler and saving you money. Live bacteria have a tough journey to make. Your stomach is highly acidic (around pH 1.5–3), which is ideal for breaking down food but can also destroy delicate bacteria, so by the time many supplements reach the intestine, very few live bacteria remain. Epetōme’s dual capsule is designed to protect them on that journey. The outer capsule shields the inner capsule from stomach acid, and the inner capsule keeps the bacteria safe until they reach the less acidic pH of the intestine. Independent laboratory testing showed greater bacterial survival than the non-encapsulated format tested, so you’re paying for protection that helps more of those live bacteria reach their destination.
Getting there alive is only half of it. Live bacteria also need something to feed on once they arrive, which is why Epetōme includes FOS, a plant-based prebiotic fibre. It passes through the stomach and small intestine undigested and reaches the lower gut, where beneficial bacteria use it as food. Many probiotic supplements stop at the bacteria alone, but Epetōme pairs them with their fuel.
Then there’s your gut lining, a single layer of cells that lets nutrients through while helping to keep out unwanted substances. That’s why Epetōme also includes zinc, biotin and vitamin D, nutrients involved in maintaining a healthy gut lining, so the live bacteria, their fuel and gut lining support come together in one daily capsule.
How soon should I be expecting to see results?
Everyone’s starting point is different. Some notice changes like reduced bloating or more regular digestion within days, while for others, it can take weeks or even months. Long-term benefits, like immune and skin health, take time and may not always be something you ‘feel’ - but that doesn’t mean the duo cap isn’t working.
Stay consistent, and give time to the beneficial microbes to improve your gut health.
Are there any side effects from taking the synbiotic duo cap?
Our gut microbiome is as unique as our fingerprint, therefore your experience with our products will be unique to you. Whilst there should be no adverse effects, some people have reported experiencing an upset stomach, gas, diarrhea, bloating or mild skin breakouts. Those symptoms usually go away after your body gets used to the bacteria in the synbiotic duo cap (usually within 1-4 weeks). However, if the problem persists, please stop taking immediately and consult your GP.
What can I expect from taking the Synbiotic dual cap?
Our carefully designed supplements can lead to various changes in your digestive system over time. We only use high-quality live cultures backed by credible science in state-of-the-art encapsulation to bring you a product you can trust. In the first few days, your body starts getting acquainted with these new guests. It's a time of gentle adjustment. I encourage you to allow your body to get used to the shift. Over the first month, you might notice changes in your digestive routine. It's your body naturally responding to your diet. By 3 months in, your body will adapt and find tempo and balance. Epetome is best taken on an ongoing basis as part of a daily health regime, making sustainable gut health habits an effortless part of your daily routine. Remember, your journey is as unique as you are. It's about consistently nourishing the friendly bacteria in our guts regularly.
Can I take these if I'm pregnant or breastfeeding?
As with any dietary supplement or new health protocol contemplated during pregnancy or breastfeeding, we recommend speaking with your GP before you start consuming our synbiotic duo cap. However, probiotics, in general, do not appear to pose any safety concerns during pregnancy or breastfeeding.
I don’t eat breakfast / practice intermittent fasting. When should I take the duo cap?
We recommend you take a capsule 20-30 minutes before food, ideally first thing in the morning. However, if you fast or don’t usually eat breakfast, we recommend taking them 20-30 minutes before your first meal of the day. The important thing is to take them at a consistent time, therefore choose a routine that works for you.
What exactly is our microbiome?
Your microbiome is a complex community of over 38 trillion microorganisms. Interestingly, there are more microbes than there are human cells in your body. You are, quite literally, more bacteria than you are you.
Scientists are still mapping out just how far this network reaches, and it has become one of the most heavily researched areas in modern science. Just over ten years ago, most people would have laughed off the idea that your gut has anything to do with your mood. Now research is constantly exploring its links to digestion, to the immune system, to hormones, to skin and to mental wellbeing.
We want to share that knowledge with our community, which is why we’ve brought together a panel of experts to make this complex area of science understandable.
We also want to stay at the forefront of this research, so we're investing in our own clinical trials to help find answers that can make a real difference to our community.
What’s the difference between a prebiotic and a probiotic?
Probiotics are live bacteria, the good kind your gut relies on. They help maintain a balanced microbiome, supporting overall gut health. You'll find them naturally in fermented foods like yoghurt, kefir and sauerkraut. But live bacteria can't do much on their own; they need something to feed on to survive and thrive, and that's where prebiotics come in.
A prebiotic is essentially food for those bacteria, usually fibre, the kind your body can't digest itself, but your gut bacteria can. You'll find it in things like fruit, vegetables, whole grains, nuts and seeds. So put simply, a probiotic is the bacteria, a prebiotic feeds it.
Should I take a supplement for my gut health?
Your gut health isn't only connected to digestion, it also plays a role in your skin, immunity, hormones, and even your mood. And it's shaped by more than just what you eat. Stress, sleep, and movement all leave their mark too, shifting your gut microbiome constantly, often without you noticing.
No two routines look the same. Maybe you eat well most of the time, but a stressful few weeks or a run of bad sleep throws things off. Or maybe it's less about food and more about a busy schedule that leaves little room for rest or movement. Either way, a balanced diet is a good foundation, but it's rarely the whole picture.
That's why a supplement isn't about replacing a good diet, but supporting your gut alongside it, whatever the week looks like. Our synbiotic dual cap is designed to complement a balanced diet. Fifty billion live bacteria from eleven strains, FOS fibre to help feed them, and nutrients such as zinc, vitamin D and biotin, carefully picked for their emerging research into gut lining support.
What makes our synbiotic dual cap unique?
Our synbiotic dual cap is a blend of science and nature, carefully formulated around the research behind each individual strain. Let's explore its unique composition.
The inner core contains 50 billion colony forming units of live bacteria, ensuring a potent and deliberate dose.
Among the eleven strains is Lactobacillus acidophilus NCFM, one of the world’s most extensively studied strains of acidophilus, with over 45 published clinical trials exploring its role in digestive comfort. Once released, the FOS fibre in the liquid part of the capsule acts as food for the live bacteria and is exactly what makes a synbiotic different from a probiotic alone.
We’ve also included three additional nutrients, Vitamin D, Biotin, and Zinc for their connection to the health of the gut lining.
Zinc contributes to the normal function of the immune system.
Biotin contributes to the maintenance of normal skin and to normal psychological function. And vitamin D3, sourced from a plant, contributes to the normal function of the immune system.
We made sure to only include ingredients that are well researched and well evidenced. But we didn't stop there.
We wanted a delivery system that ensured what's inside the synbiotic dual cap gets to your gut alive. Our unique dual cap delivery system has one of the greatest survivability rates, with an outer core to protect the strains through the stomach, helping far more of them survive the journey and actually arrive where they're meant to.
What can I expect from taking the synbiotic dual cap?
We only use high quality live cultures backed by credible science in state of the art encapsulation to bring you a product you can trust.
In the first few days, your body is simply getting acquainted with something new. It is a time of gentle adjustment, and that is completely normal. Any new addition to your routine takes a little time to settle, and this one is no different. I always encourage people to give it that space rather than looking for anything overnight.
Over the first month, you might notice things starting to shift in your daily routine. It will look different for everyone.
By three months in, your gut should be accustomed to the live bacteria and you’ve started finding your tempo. Because the live bacteria are transient, it is their regular, daily presence that matters most, which is why Epetōme is designed to be taken on an ongoing basis as part of a daily routine, making a consistent gut health habit an effortless part of your morning.
You only have to read through our reviews to see how it has become a non-negotiable for people's daily lives.
Why does survivability matter and how does the synbiotic dual cap achieve it?
Most live bacteria supplements face the same problem. The journey through the stomach is an acidic one, and a lot of bacteria do not survive it. So the number on the label and the number that actually arrives can tell a very different story. And for us, that gap is exactly where the Dual Cap begins.
Rather than a single standard capsule, ours works in two stages. The outer core protects the bacteria through the stomach, releasing them only once they reach the part of the gut where they are actually meant to be.
That is what makes survivability so central to how we think about bacterial composition, because the best strains in the world only matter if they get there.
We tested this using SHIME, a validated gut model used by research institutions around the world. Against non-encapsulated formats, our dual cap delivered up to 23x higher survivability. Even accounting for the natural dropout that happens on that journey, our survivability rate is high enough that we arrive with more than most formats start with. That is the difference between a number on a label and a number that actually reaches your gut.
customer reviews.
our unique formulation.
Our capsule contains 11 unique bacterial strains from 7 different species. They have each been carefully selected and are all trademarked and registered. In amongst them, we are proud to include Lactobacillus acidophilus NCFM, the world's most researched strain of acidophilus.
Paired with FOS fibre and key nutrients, all contained within our state-of-the-art synbiotic dual cap, we ensure the targeted delivery of ingredients to the right place, at the right time.
LEARN MORE
15 active ingredients.
Fructooligosaccharides (FOS) act as the food and energy source for the live bacteria in our capsule. Housed within the liquid layer, it is released first to support the function of the live inner core.
READ MORE ON FOS
Bifidobacterium lactis HN019
12.88 billion CFU
This particular bifidobacterium has many clinical trials exploring its ability to help with digestive issues like constipation.
View Studies
Del Piano, M., Carmagnola, S., Anderloni, A., et al. (2010).
The Role of Probiotics in Improving Gut Health in Healthy Volunteers with Evacuation Disorders and Hard Stools. Journal of Clinical Gastroenterology, 44(Suppl 1), S30-S34.
Waller, P.A., Gopal, P.K., Leyer, G.J., ET AL. (2011).
Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults. Scandinavian Journal of Gastroenterology, 46(9), 1057–1064.
Lactobacillus acidophilus NCFM
10 billion CFU
We are proud to include the world's most researched strain of acidophilus. Many studies explore its link with IBS-related pain, bloating, immune support, cognition and skin health.
View Studies
Magro, D.O., de Oliveira, L.M., Bernasconi, I., et al. (2014).
Efficacy of probiotic supplementation for constipation relief.International Journal of Gastroenterology and Hepatology, 59(1), 15-19.
Paineau, D., Carcano, D., Leyer, G., et al. (2008).
Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial.Journal of Clinical Immunology, 28(6), 542-551.
Lactobacillus plantarum LP-115
8 billion CFU
LP-115 has been tested on its potential to promote beneficial effects in the immune system and alleviate intestinal disorders.
View Studies
Tian, L., Zhao, R., Xu, X. et al. 2023.
Modulatory effects of Lactiplantibacillus plantarum on chronic metabolic diseases. Food Science and Human Wellness.
Lactobacillus rhamnosus GG
7.11 billion CFU
Lactobacillus rhamnosus GG appears in trials on conditions such as diarrhea, inflammatory bowel disease, atopic dermatitis, and even dental caries.
View Studies
Steele, C. (2022).
Lactobacillus rhamnosus GG: a review of clinical use and efficacy. Nutr. Med. J., 1(3), 70-116.
Bifidobacterium breve BB18
4.66 billion CFU
Bifidobacterium breve Bb-18 has been tested for its role in supporting the maturation and maintenance of the immune system within the gut. Research indicates that it is associated with increased resistance to infections and enhanced immune activity.
View Studies
Arreola, S. L., Intanon, M., Suljic, J., et al. (2014).
Two β-Galactosidases from the Human Isolate Bifidobacterium breve DSM 20213: Molecular Cloning and Expression, Biochemical Characterization and Synthesis of Galacto-Oligosaccharides. PLOS ONE, 9(8), e104056.
Bifidobacterium lactis BL04
3.25 billion CFU
This strain has been tested in a broad range of areas, including improving intestinal barrier function, regulating immune defence, reducing the incidence of diarrhoea and associations with the gut-brain axis.
View Studies
Wang Y, Li N, Yang J.J. et al. 2020.
Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder.
Forssten S.D., Yeung N., Ouwehand A.C. 2020.
Fecal Recovery of Probiotics Administered as a Multi-Strain Formulation during Antibiotic Treatment.
Lactobacillus rhamnosus HN001
1.2 billion CFU
Lactobacillus rhamnosus HN001 has demonstrated potential to enhance immune function and increase natural cellular immune responses. It has also demonstrated potential to improve skin conditions like eczema.
View Studies
Barthow, C., Hood, F., Crane, J., et al. (2022).
A randomised controlled trial of a probiotic and a prebiotic examining metabolic and mental health outcomes in adults with pre-diabetes. BMJ Open, 12:e055214.
Bonfrate L, Di Palo DM, Celano G, et al.
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50(3):e13201.
Bifidobacterium bifidum BB-06
0.88 billion CFU
Bifidobacterium bifidum BB-06 has been tested mostly around its ability to support the gut-brain axis and gut-skin axis, two growing research areas in gut health.
View Studies
Ferro, M., Charneca, S., Dourado, E., Guerreiro, C.S., Fonseca, J.E. (2021).
Probiotic Supplementation for Rheumatoid Arthritis: A Promising Adjuvant Therapy in the Gut Microbiome Era. Front. Pharmacol., 12:711788.
Lacticaseibacillus paracasei LPC37
0.88 billion CFU
Lacticaseibacillus paracasei Lpc-37 is well-researched for its role in supporting digestive health and has also been studied for its potential to help manage the psychological response to stress.
View Studies
Ouwehand AC, DongLian C, Weijian X, et al.
Probiotics reduce symptoms of antibiotic use in a hospital setting: a randomized dose response study. Vaccine. 2014;32:458-463.
Bifidobacterium longum BL05
0.88 billion CFU
Bifidobacterium longum BL-05 has more limited research but has shown promising results, including measurable changes in gut microbiome composition, improvements in symptoms like constipation, bloating, diarrhoea, and abdominal discomfort.
View Studies
hen, S., Jiang, P.-P., Yu, D., et al. (2021).
Effects of probiotic supplementation on serum trimethylamine-N-oxide level and gut microbiota composition in young males: A double-blinded randomized controlled trial. Eur. J. Nutr., 60(2), 747–758. doi: 10.1007/s00394-020-02278-1.
Lactobacillus acidophilus LA14
0.26 billion CFU
Lactobacillus acidophilus LA14 has been tested on its role in immune function and modulation, and some limited tests into its ability to improve cognitive function.
View Studies
De Nunzio, C., Bartoletti, R., Tubaro, A. et al. (2021).
Role of D-Mannose in the Prevention of Recurrent Uncomplicated Cystitis: State of the Art and Future Perspectives. Antibiotics, 10, 373.
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